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diclofenac) Good anti-inflammatory and analgesic effect Side effects Common Dyspepsia Abdominal pain Nausea Diarrhea Serious Peptic ulcer & GI bleeding Acute kidney injury Elevated liver enzymes Fluid retention, edema Hypertension Contraindications Active peptic ulcer disease Severe renal or hepatic impairment NSAID hypersensitivity / aspirin-induced asthma Third trimester of pregnancy Drug interactions Anticoagulants bleeding risk ACE inhibitors / diuretics renal toxicity Other NSAIDs GI toxicity Aceclofenac is a diclofenac derivative Less gastric irritation but NOT GI-safe Avoid in CKD and late pregnancy No disease-modifying effect in arthritis (symptomatic relief only) To view or add a comment, sign in NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) NSAIDs are medications used to relieve pain, reduce inflammation, and lower fever by inhibiting prostaglandin synthesis

as for patients with neurological improvement, 1 mg IM OH-Cbl on alternate days until there is no clinical improvement and then maintenance 1 mg IM OH-Cbl every 2 months is recommended (NICE, 2022)

It is important to adopt a healthy, well balanced diet which pays attention to the nutrient deficiencies commonly associated with Parkinsons, such as vitamin B12

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Anyone experiencing fatigue, low energy, brain fog, or known B12 deficiency may benefit